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2017

Alsafadi HN, Staab-Weijnitz CA, Lehmann M, Lindner M, Peschel B, Königshoff M, Wagner DE. An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices. American Journal of Physiology - Lung Cellular and Molecular Physiology (2017)

Knüppel L, Ishikawa Y, Aichler M, Heinzelmann K, Hatz R, Behr J, Walch A, Bächinger HP, Eickelberg O, Staab-Weijnitz CA. A Novel Antifibrotic Mechanism of Nintedanib and Pirfenidone: Inhibition of Collagen Fibril Assembly. Am J Respir Cell Mol Biol. (2017)

Skronska-Wasek W, Mutze K, Baarsma HA, Bracke KR, Alsafadi HN, Lehmann M, Costa R, Stornaiuolo M, Novellino E, Brusselle GG, Wagner DE, Yildirim AÖ, Königshoff M. Reduced Frizzled Receptor 4 Expression Prevents WNT/β-catenin-driven Alveolar Lung Repair in COPD. American Journal of Respiratory and Critical Care Medicine (2017)

Baarsma HA, Skronska-Wasek W, Mutze K, Ciolek F, Wagner DE, John-Schuster G, Heinzelmann K, Günther A, Bracke KR, Dagouassat M, Boczkowski J, Brusselle GG, Smits R, Eickelberg O, Yildirim AÖ, Königshoff M. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J Exp Med (2017)

2016

Bartmann J, Frankenberger M, Neurohr C, Eickelberg O, Nößner E, von Wulffen W. A novel role of MMP-13 for murine DC function: Its inhibition dampens T cell activation. Int. Immunol. 28, 473-487 (2016)

Chen S, Yin R, Mutze K, Yu Y, Takenaka S, Königshoff M, Stöger T. No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in mice. Part. Fibre Toxicol. 13:33 (2016)

Dietz K, de los Reyes Jimenez M, Gollwitzer ES, Chaker AM, Zissler UM, Rådmark, OP, Baarsma HA, Königshoff M, Schmidt-Weber CB, Marsland BJ, Esser-von Bieren J. Age dictates a steroid resistant cascade of Wnt5a, transglutaminase-2 and leukotrienes in inflamed airways. J. Allergy Clin. Immunol., DOI: 10.1016/j.jaci.2016.07.014 (2016)

Kammerl IE, Dann A, Mossina A, Brech D, Lukas C, Vosyka O, Nathan P, Conlon TM, Wagner DE, Overkleeft HS, Prasse A, Rosas IO, Straub T, Krauss-Etschmann S, Königshoff M, Preissler G, Winter H, Lindner M, Hatz RA, Behr J, Heinzelmann K, Yildirim AÖ, Nößner E, Eickelberg O, Meiners S. Impairment of immunoproteasome function by cigarette smoke and in COPD. Am. J. Respir. Crit. Care Med. 193, 1230-1241 (2016)

Kepert I, Fonseca J, Müller C, Milger K, Hochwind K, Kostric M, Fedoseeva M, Ohnmacht C, Dehmel S, Nathan P, Bartel S, Eickelberg O, Schloter M, Hartmann A, Schmitt-Kopplin P, Krauss-Etschmann S. D-Tryptophan from probiotic bacteria influences the gut microbiome and allergic airway disease. J. Allergy Clin. Immunol., DOI: 10.1016/j.jaci.2016.09.003 (2016)

Klee S, Lehmann M, Wagner D, Baarsma HA, Königshoff M. WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts. Sci. Rep. 6:20547 (2016)

Mummler C, Vierkotten S, Mutze K, Günther A, Königshoff M. Runt-related transcription factor 2 (runx2) regulates mesenchymal cell differentiation and extracellular matrix production in pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 193 (2016)

van Rijt SH, Bölükbas DA, Argyo C, Wipplinger K, Naureen M, Datz S, Eickelberg O, Meiners S, Bein T, Schmid O, Stöger T. Applicability of avidin protein coated mesoporous silica nanoparticles as drug carriers in the lung. Nanoscale 8, 8058-8069 (2016)

Yaroshenko A, Pritzke T, Koschlig M, Kamgari N, Willer K, Gromann L, Auweter S, Hellbach K, Reiser M, Eickelberg O, Pfeiffer F, Hilgendorff A. Visualization of neonatal lung injury associated with mechanical ventilation using X-ray dark-field radiography. Sci. Rep. 6:24269 (2016)