Logo Helmholtz Zentrum München

Introduction to translational lung research

Introductory seminars through which students acquire the necessary basic knowledge and awareness of important general scientific issues before starting their research project. All of the following courses are mandatory.

Good Scientific Practice: Overview of the recommendations given by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) in "Safeguarding Good Scientific Practice", which covers topics such as: Rules and regulations, ombudsmen, supervision, quality vs. quantity, data handling, publishing, funding, confidentiality. Courses are offered regularly by the MMRS and the CPC Research School.

Research Ethics: Interactive course that addresses major research ethical problems and concepts, such as autonomy and informed consent, scientific fraud and misconduct, the researcher's responsibility for the consequences of their research, and the protection of human subjects. Courses are offered once a year by the CPC Research School.

Lab Safety Training: Laboratory safety training (incl. rules and guidelines, procedures, information on health and safety hazards, etc.) is required before beginning to work in the lab. This component is given regularly by the CPC Safety Team.

Fundamentals of Lung Biology and Physiology: Introductory module aiming at familiarizing students from different scientific and academic backgrounds with lung biology and physiology. The seminar takes place at the very beginning of the doctoral studies and lays the foundation for the research project and covers lung anatomy and histology, lung physiology, lung biology, and an introduction to lung diseases.

Methods in Translational Research: MD and PhD students present fundamental biomedical methods and technologies, which they will use within the framework of their work. Topics and content are added on a relevant basis and include: Animal models, cell and tissue culture, functional analysis and cellular imaging, flow cytometry, immunohistochemistry, immunofluorescence, generation of antibodies, microscopy, nucleic acid analysis, protein analysis, protein-DNA interaction, protein-protein interaction, screening animals, transgene animals and knockout animals. This presentation will be graded and constitutes 20% of the final grade for the introductory module.

Project Design & Presentation: Students should present an outline of their MD or PhD work that they will pursue, i.e. defining clear research questions and the approaches which will be used to answer them, highlighting originality/significance of the project, and explaining how the project adds to, develops or challenges existing literature in the field.

Written Examination: The objective of the exam is to assess the progress made by the students towards attaining the skills and knowledge described above which are necessary for completing the MD or PhD. Outstanding exams are awarded with a travel grant to help offset costs associated with the attendance at a conference of their choice. The exam is comprised of content from the Fundamentals of Lung Biology and Physiology and Methods in Translational Research. The written exam will constitute 80% of the final grade for the introductory module.

To proceed with the Research School curriculum, students need to pass the introductory module with >65%. The grade is comprised of 20% from the Methods presentation and 80% from the written exam.